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Dr. Fefferman?s research interests have focused on optimizing techniques for ionizing radiation dose reduction in pediatric CT and computed radiography. This is of particular importance in view of the potential carcinogenic effects of radiation in children.

We have recently developed a method for realistic simulation of increased CT image noise. We plan to demonstrate the utility and feasibility of this phantom-based simulation technique as a means of optimizing pediatric multi-detector CT tube current and subsequent dose reduction.

Using this innovative image simulation technique, our research will focus on establishing low dose protocols for pediatric multi-detector abdominal/pelvic and chest CT. Early results have been promising in the evaluation of low dose CT imaging for appendicitis using the simulation methodology.